I am a Transportation Network Company Driver (Uber, Lyft, Etc.) based out of the City of Santa Ana, but I do business throughout Southern California. Do I need to get a business license?

Yes, if you are a Transportation Network Company Driver based out of the City of Santa Ana receiving a 1099 Form, you must obtain a flat rate City Santa Ana Business License as an independent contractor. Note: once licensed in your home-based city you are not required to obtain a business license in the other California cities in which you operate.